GLASSY SKIN CLINIC · DERMATOLOGY · CHEONGDAM, SEOULDr. JudyEN
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Collagen & Skin Boosters

Re2O

Re2O in Seoul — tissue-derived skin-quality care

A material made from processed human acellular dermal matrix: a tissue-derived scaffold, rather than living donor cells. The processed tissue provides a collagen-containing structural material; it does not add living donor cells.

It may be considered for skin quality, texture and fine lines in an individual plan. At Glassy, your dermatologist plans the area, intensity or product around your skin and goals, with comfort considered throughout.

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A closer look

Meet the products.

Explore the products used in this treatment. Select a product to see its components and how it works.

Elravie Re2O product

Components & how it works

Elravie Re2O

Human acellular dermal matrixCollagen scaffold

Re2O (Elravie Re2O) was developed by L&C Bio [5] and is distributed in Korea by Humedix. [6] In Korea it is regulated as a human tissue product, not a drug or medical device, under human tissue rules overseen by the MFDS rather than a separate product approval. [7][8] It supplies a collagen scaffold directly to the skin. In a small split-face trial of 20 adults, an hADM booster (brand not named) improved skin density, elasticity and wrinkles more than hyaluronic acid. [9]

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Re2O at a glance

  • Product / approach:
    Human acellular dermal matrix
  • May help with:
    skin quality, texture and fine lines in an individual plan.
  • Areas:
    Selected facial areas; placement depends on skin thickness and the concern.
  • Comfort:
    Brief injection discomfort or pressure. Comfort measures depend on the area and method.
  • Performed by:
    A board-certified dermatologist (Korea).
  • Downtime:
    Red marks, small bumps, swelling or bruising may follow injections.

How we do it at Glassy Skin Clinic

  • In English:
    Our board-certified dermatologists, Dr. Judy, Dr. Max, Dr. Sunny and Dr. Sophie, consult and treat in English.
  • No sedation:
    We adjust comfort as we go. Brief injection discomfort or pressure. Comfort measures depend on the area and method.
  • Careful preparation:
    We assess your skin, check previous treatments and agree the treatment area and comfort plan before starting.
  • The right tool:
    Your dermatologist explains the tissue-derived material and selects a suitable delivery approach.
  • A private room:
    Time is planned for assessment, preparation and treatment in a private room. Confirm your total appointment time with the clinic.
From the clinic’s reviewed guide

Re2O (Elravie Re2O) is a Korean skin booster made with collagen from human acellular dermal matrix, or hADM. It was developed by L&C Bio [1] and is distributed in Korea by Humedix. [2] In Korea, Re2O is classified as a human tissue product rather than as a drug or medical device, so it is managed under human tissue rules overseen by the Ministry of Food and Drug Safety (MFDS) instead of going through a separate product approval. [3][4]

Most skin boosters work by prompting your skin to respond: to make more collagen, to hold more water, or to repair itself. Re2O takes a different approach. It delivers a collagen scaffold directly into the skin. [5]

I'm Dr. Judy (Hong Jin Joo), a board-certified dermatologist in Cheongdam, Seoul. Re2O is one of the two options in our GLT™ Collagen Healer program, and patients often ask how it compares with better-known names like Juvelook and Rejuran.

At our clinic, Re2O is delivered as GLT™ Collagen Healer with Re2O, using GLT™ (Gentle Layered Treatment), our clinic's own layered treatment method.

  • Layered placement: product is spread in thin layers across the dermis rather than concentrated in one spot.
  • Hycoox 9-needle injector: at our clinic, Re2O is delivered with the Hycoox multi-needle injector, the same tool we use for skin-layer Juvelook.
  • Delivery matched to your concern: depending on your skin concern, we can also deliver Re2O with the needle-free CureJet injector or with Potenza RF microneedling.
  • No sedation: you stay awake, and your dermatologist adjusts as you go (comfort and pain control).
  • Board-certified dermatologists only: Dr. Judy, Dr. Max, Dr. Sunny or Dr. Sophie performs every treatment.
  • Private room, unhurried visits: at our clinic, appointments usually run 1 to 3 hours, including consultation and aftercare.

You can read more on our Re2O treatment page.

Read the clinic guide

Who is it for?

It may suit you if you are looking for help with:

  • skin quality, texture and fine lines in an individual plan.
  • Selected facial areas; placement depends on skin thickness and the concern.

It is not a stem-cell treatment. Tell the doctor about previous reactions and medical conditions.

For the clinic’s skin-quality programme, see GLT™ Collagen Healer.

Downtime, aftercare and side effects

  • Downtime:
    Red marks, small bumps, swelling or bruising may follow injections.
  • During treatment:
    Brief injection discomfort or pressure. Comfort measures depend on the area and method.
  • Aftercare:
    Ask about skincare, exercise and pressure on the treated area before leaving. Follow the instructions for your actual procedure rather than another treatment’s routine.
  • If you are concerned:
    Contact the clinic if symptoms are worsening or do not match the advice you were given.

Who should not have it?

Your dermatologist checks suitability before treatment. Tell us if you:

  • Have an active infection, broken skin or a new unexplained rash in the area.
  • Have a known allergy to a proposed product or numbing medicine.
  • Take medicines, have a medical condition, or have had recent treatment in the same area.
  • Are pregnant or breastfeeding. Your doctor will discuss whether to postpone the proposed procedure.

It is not a stem-cell treatment. Tell the doctor about previous reactions and medical conditions.

How much does it cost?

We confirm your exact price at consultation, before any treatment. All our prices include 10% VAT.

Your plan depends on the area, product or device, and any combined care. Ask the clinic for the total before deciding.

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Your questions

Frequently asked questions

What is Re2O?

A material made from processed human acellular dermal matrix: a tissue-derived scaffold, rather than living donor cells. The processed tissue provides a collagen-containing structural material; it does not add living donor cells.

Is Re2O the same as Juvelook?

No. Re2O is tissue-derived; Juvelook contains PDLLA and hyaluronic acid. The choice depends on your skin and goals.

How many sessions will I need?

The number of visits and spacing are personalized. We discuss a starting plan and review your response before recommending further treatment.

Can I combine it with another treatment?

Tell the clinic what you have recently had and what you are planning. Combining procedures is a separate decision; it depends on your skin, the products and the time available for recovery.

References

Product and treatment information from the sources below, checked 28 October 2026. Manufacturer descriptions explain the technology; they do not promise an individual result. Product uses and authorization differ by country.

  1. Humedix · Elravie Re2O

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