The Glassy perspective
Skin insights from our dermatologists.
Stories behind our approach to care.
A good place to begin.
Skin Insights
Juvelook and Juvelook Volume use the same collagen-stimulating ingredient (PDLLA with hyaluronic acid) but do different jobs. Juvelook has smaller particles and goes into the shallow skin layer for fine lines, rough texture, dryness and glow. Juvelook Volume, sold as Lenisna in some markets, has larger particles, goes deeper and is used for hollows such as the tear trough and mid-cheek.
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Skin Insights
Re2O (Elravie Re2O) is a Korean skin booster made with collagen from human acellular dermal matrix (hADM). It was developed by L&C Bio and is distributed in Korea by Humedix. In Korea it is regulated as a human tissue product rather than as a drug or medical device. Instead of mainly prompting your skin to make collagen, as Juvelook does, Re2O supplies a collagen scaffold directly to the skin. At Glassy Skin Clinic it is delivered as GLT™ Collagen Healer with Re2O.
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GLASSY Story
Your preferred treatment is a starting point for a conversation. At Glassy, the plan takes shape around your skin, your priorities and what is appropriate for you now.
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GLASSY Story
A consultation can lead to a decision to postpone a procedure. At Glassy, that discussion is part of choosing care around your current skin rather than a predetermined treatment.
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GLASSY Story
Bring your concerns and questions to your first visit. This introduction explains the conversations to prepare for, while practical arrival information stays in our Plan Your Visit guide.
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Skin Insights
Juvelook is a Korean collagen-stimulating injectable made of PDLLA (poly-D,L-lactic acid) and non-crosslinked hyaluronic acid. Rather than filling a line directly, it encourages your skin to build its own collagen over the following months. Juvelook is used for skin quality; Juvelook Volume is the version used to restore lost volume. It is approved in Korea but not FDA-approved in the US.
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Skin Insights
Juvelook is a family of PDLLA + hyaluronic acid collagen stimulators made by Vaim in Korea. Juvelook i, Juvelook Skin and Juvelook go into the dermis to improve skin quality and fine lines; Juvelook Volume 100, Juvelook Volume (sold as Lenisna in some countries) and Juvelook G go deeper to restore lost volume. Juvelook Shine is different: it's a topical skincare product, not an injection.
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Skin Insights
Juvelook's PDLLA particles set off a controlled response in the skin in which repair-type (M2) immune cells play a central role. According to the manufacturer and an animal study in aged mice, these cells release IL-10, which supports stem cells and fibroblasts that make new collagen and elastin, while collagen-breaking enzymes (MMPs) go down. Most of this mechanism comes from animal and lab studies, so results in people build gradually and vary.
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Skin Insights
Even one Juvelook session gives results, and repeated sessions build on it: the manufacturer's standard course for Juvelook and Juvelook Volume is three sessions. Vaim's 2023 English brochure spaces them about 1 month apart, while Vaim's UK partner lists 6 weeks for Juvelook and 8 weeks for Lenisna (Juvelook Volume). At our clinic, Juvelook is planned as 3 or more sessions 1–3 months apart, and Juvelook Volume as usually 3 sessions 6–12 weeks apart.
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Skin Insights
Juvelook comes as a dry powder of PDLLA particles and hyaluronic acid, and it has to be fully hydrated so the particles are evenly suspended before injection. For same-day preparation, Vaim's 2023 English brochure specifies 30 minutes on a vortex mixer; other official documents describe other routes to the same even suspension. Even suspension matters because the manufacturer describes nodules as clumped ("massed") particles.
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Skin Insights
No — as long as you receive the same vial or vials. Adding liquid to Juvelook spreads the same amount of PDLLA more evenly; it doesn't take any product away. The manufacturer's public English brochure lists 6 mL for the 50 mg Juvelook vial and 8 mL for the 200 mg Juvelook Volume (Lenisna) vial, so a number of mL only means something when you also know the vial.
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Skin Insights
Nodules after Juvelook are uncommon and are usually small clumps of PDLLA particles. Early bumps in the first days are usually swelling that settles on its own; a firm lump that persists for weeks should be examined. Because hydrated PDLLA softens at about 39°C, the manufacturer describes managing a nodule with extra saline, gentle heat from an energy-based device, and pressure — usually without surgery.
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Skin Insights
Juvelook and Juvelook Volume don't come with a daily home-massage routine like Sculptra's "5-5-5" rule (5 minutes, 5 times a day, for 5 days). Vaim's official UK partner, FILLMED, recommends a single firm 1–2 minute massage right after injection to disperse the product. At our clinic, right after Juvelook Volume, a nurse trained by our dermatologists shows you how to massage the area firmly for 1–2 minutes, and your dermatologist checks once more that you're doing it correctly; for skin-layer Juvelook, massage is optional.
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Skin Insights
Juvelook Volume and Sculptra are both collagen stimulators, but they use different ingredients. Juvelook Volume (sold as Lenisna in some countries) combines porous, spherical PDLLA (poly-D,L-lactic acid) particles with non-cross-linked hyaluronic acid, while Sculptra uses PLLA (poly-L-lactic acid) reconstituted with sterile water. Both work gradually over several weeks. Sculptra's official aftercare is a 5-day home massage routine; Juvelook Volume has no daily routine, just one short massage right after injection.
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Skin Insights
Juvelook prices in Seoul vary because clinics quote different things: the amount of product in cc, who performs the treatment, how much time is spent with the doctor, numbing and cannula use, aftercare, post-treatment skin care and whether 10% VAT is included. Comparing these items side by side tells you more than comparing headline prices. For Glassy Skin Clinic's own prices, see our Juvelook price page.
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Skin Insights
The 1 cc Juvelook price you often see in other clinics' quotes is for a small, targeted area, such as a few deep acne scars or a single wrinkle. It can't treat a whole face. Full-face skin-quality treatment usually needs about 3–5 cc; at Glassy Skin Clinic, full-face GLT™ Collagen Healer with Juvelook uses 4 cc (Essential) or 5 cc (Signature). Because "cc" also depends on how the vial was diluted, compare vials and technique, not just cc.
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Skin Insights
Under-eye fine lines are a skin-quality problem, while hollows and tear troughs are a volume problem, so they are treated differently. At Glassy Skin Clinic, we treat fine lines and crepey texture with GLT™ Collagen Healer with Juvelook, placed in the shallowest skin layer with a 9-needle injector. We treat hollows and tear troughs with GLT™ Collagen Volume Lifting with Juvelook Volume, using a blunt cannula, usually together with the mid-cheek. Both can be done on the same day, because they go into different layers.
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Skin Insights
The under-eye and the mid-cheek are anatomically connected, and in our clinic's experience most people with under-eye hollows also have some mid-cheek hollowing. That's why at Glassy Skin Clinic we rarely treat the under-eye alone. We usually treat both areas together with GLT™ Collagen Volume Lifting with Juvelook Volume, for a more natural, continuous result.
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Skin Insights
Skin-layer Juvelook (GLT™ Collagen Healer with Juvelook) can be used even where you've had hyaluronic acid (HA) filler. Juvelook Volume is different: it goes into the upper fat layer, where HA filler may still sit, so at our clinic we don't treat an area with Juvelook Volume while filler remains there. If you've had filler at any time and none remains on palpation or ultrasound, we treat only after you sign a consent that swelling may last longer than usual. If your filler was dissolved, we wait at least 6 months; please tell us your filler history before you book.
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